Author: Sandy Hutchison

Therapeutic proteins are exposed to stress during the manufacturing process and can aggregate to form particles. These protein aggregate particles can induce adverse immune responses in patients. This paper discusses the use of image compression techniques proven in facial recognition …

Compendial methods for the analysis of subvisible particles in protein drugs are inadequate. New techniques, like flow-imaging microscopy (FIM), show promise but require subjective, qualitative manual identification. These manual methods ignore relevant structural or morphological information embedded in the images. …